In normal mode, you're basically invulnerable until you run out of stimpacks. This is the biggie - all the rest of the changes combined won't affect you as much as one. More like 'HELL Yes!' 1: Stimpacks don't heal instantly
What's Hardcore mode, and are you hardcore enough to play it? Don't jump in blind: read our guide to the five big differences, and tips for how to survive the increased deadliness of the Hardcore Nevada wastes.